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KMID : 0362220120390040311
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Journal of The Korean Research Society for Dental Materials
2012 Volume.39 No. 4 p.311 ~ p.318
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Evaluation of Dental Composite Dispersed with Silver-Doped Phosphate Antibacterial Glasses
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Moon Ho-Jin
Ahmed El-Fiqi
Cha Jae-Ryung
Lee Sung-Hoon
Gong Myoung-Seun
Kim Hae-Won
Baek Dong-Heon
Shin Dong-Hoon
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Abstract
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The purpose of this study was to investigate the effect of adding antibacterial silver-doped phosphate glasses on the antibacterial properties of conventional dental composite. Silver-doped phosphate antibacterial glasses were prepared by the melting method. The antibacterial effects of some undoped and silver-doped glasses of composition , (where x=0, 1, 1.5, 2 mol %), against Staphylococcus aureus, Escherichia coli and Streptococcus mutans micro-organism using agar diffusion test and mininum inhibitory concentration test were investigated. A visible light system of camphorquinone photo-initiator and 2-(dimethylamino)ethyl methacrylate photo-accelerator was utilized to activate the resin matrix in the polymer composites. The degree of conversion, depth of cure, mechanical strength and antibacterial properties of dental composites with glass powder and resin matrix were investigated. Silver-doped glasses showed an increase in inhibition zone diameter against the tested micro-organisms. Composite groups that contain small amounts of phosphate glasses (Group 0~3) demonstrated no significant difference in compressive and flexural strength, but composite that has maximum filler use with phosphate glass (Group 4) showed severe decrease in both mechanical strength. There was no signigicant difference in degree of conversion. However, there was significant decrease in depth of cure for the Group 4. Silver-doped phosphate antibacterial glasses inhibited the growth of the major oral pathogen S. mutans. But there was no significant difference in antibacterial effects when they mixed into dental composite. These results indicate that a dental resin composite with 2 % Ag-doped phosphate glass may not be useful clinically because its insufficient anticariogenic effect, even though it showed favorable mechanical strength and polymeric behavior. Further study should be needed to overcome the low antibacterial effect and to establish the effective mechanism and dynamic model for the anticariogenic composite resin.
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KEYWORD
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Anticariogenic, Composite resin, Silver-doped phospate glass, Streptococcus mutans
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